Sharyn Craig has a terrific book called "Great Sets" where she presents wonderful ideas for putting together quilt blocks into wonderful quilts. This book was a great reference for me to come up with a setting plan for the tops-to-be.
First one that was finished was a group of 30s blocks that I set with bright blue, it will be a quilt for my niece Emily.


I drew the block from Sharyn's book in Electric Quilt.

Then I decided to add a frame around the centre, to increase the size of the finished block, and so the size of the quilt.

Then I used the Serendipidity tool on the block table to merge my sampler block into the frame block

Then, I was able to play with my quilt, changing fabrics and colourings of the block. I ended up with 30 quilts in my sketchbook, and at least 10 colourings of the block! When I was done, I had Sharyn's instructions on how to create the frame, and I also had some measurements from EQ to help me with the construction.
Stitch good thoughts!